Welcome to our T-cell Mediated Cytotoxicity Assay Platform. This platform is designed to determine the extent to which test substances affect the cytotoxic/hypersensitivity reactions of target tumor cells after promoting or inhibiting T-cell activity. It offers researchers a crucial avenue to deeply understand the potential impact of their drugs on T-cell functions.
Application Areas:
• This method is particularly suitable for the immune activity detection of antibody drugs, such as bispecific antibodies (bscAb), especially antibodies in the Bispecific T-cell Engager (BiTE) subclass.
• Additionally, it provides essential support for PBMC donor screening.
Target Cell Selection:
• We present a range of choices to cater to your research needs, including tumor cell lines, primary tumor cells, and genetically engineered cell strains.
Effector Cell Provision:
• You have the option to utilize commercially sourced PBMCs or PBMCs derived from clinical patients. Our team of experts will recommend the most appropriate effector cell group based on the specific requirements of new drug development.
Analysis and Detection:
• Employing flow cytometry techniques, we accurately differentiate between effector and target cells and provide precise data on target cell counts and apoptotic cell proportions.
On this platform, we are committed to delivering the most advanced and accurate T-cell cytotoxicity assay services, propelling your research towards groundbreaking results. We look forward to collaborating with you!