创模生物科技(北京)有限公司

CN / En

NEWS

InnoModels Biotechnology: What are the advantages of genetically engineered homology models?

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-03-18 15:27
  • Views:

(Summary description)In the field of biomedicine, the establishment of disease models is crucial to drug development. In recent years, the Genetic Engineering Homology Model (GEM) of InnoModels Biotechnology has shown great potential in disease simulation and drug discovery by virtue of its unique advantages. In this paper, we will introduce the characteristics of the modeling bioengineered homology model and its application value in drug discovery and development.

InnoModels Biotechnology: What are the advantages of genetically engineered homology models?

(Summary description)In the field of biomedicine, the establishment of disease models is crucial to drug development. In recent years, the Genetic Engineering Homology Model (GEM) of InnoModels Biotechnology has shown great potential in disease simulation and drug discovery by virtue of its unique advantages. In this paper, we will introduce the characteristics of the modeling bioengineered homology model and its application value in drug discovery and development.

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-03-18 15:27
  • Views:
Information

In the field of biomedicine, the establishment of disease models is crucial to drug development. In recent years, the Genetic Engineering Homology Model (GEM) of InnoModels Biotechnology has shown great potential in disease simulation and drug discovery by virtue of its unique advantages. In this paper, we will introduce the characteristics of the modeling bioengineered homology model and its application value in drug discovery and development.
Overview of Genetic Engineering Homology Models of InnoModels Biotechnology.
Genetic engineering homology model is to introduce specific genes or gene fragments of target diseases into experimental animals through gene editing technology, so that they express disease phenotypes similar to those of human body. By simulating the gene expression in human disease states, the Genetic Engineering Homology Models of InnoModels Biotechnology provide a more realistic and accurate research environment for drug discovery and development.
Advantages of Genetic Engineering Homology Models from InnoModels Biotechnology
1. Accurate simulation of disease mechanisms: InnoModels' genetic engineering homology model can accurately simulate the pathogenesis of human diseases, including gene mutations and expression abnormalities. This provides researchers with an experimental environment that is closer to the actual disease, which helps to deeply understand the development process of the disease and provides powerful support for drug development.
2. Highly controllable: Through gene editing technology, researchers can precisely manipulate specific genes in experimental animals to realize the controlled occurrence and development of diseases. This facilitates the efficacy assessment and safety evaluation during drug development.
3. Individualized therapeutic strategies: Genetic engineering homology model of InnoModels can simulate the genetic differences between different individuals, providing powerful support for the development of individualized therapeutic strategies. It is expected to improve the therapeutic efficacy and reduce the side effects of drugs by screening and optimizing the drugs according to the genetic characteristics of different individuals.
4. Shorten the R&D cycle: Compared with traditional animal models and clinical trials, InnoModels' genetically engineered homology models are able to simulate the process of disease onset and progression faster, providing earlier efficacy assessment for drug development. This helps to shorten the drug development cycle and accelerate the process of bringing new drugs to market.

 


Application of Genetic Engineering Homology Model of InnoModels Biotechnology in drug discovery and development
1. Drug target discovery: Genetic engineering homology model of InnoModels Biotechnology can be used to study the key genes and signaling pathways in the process of disease development, which provides powerful support for drug target discovery. By analyzing the gene expression profiles and signaling pathways in the model, researchers can screen out genes and signaling pathways that are closely related to the development of diseases and provide potential targets for new drug development.
2. Drug efficacy evaluation: Genetic engineering homology model of InnoModels can be used to evaluate the efficacy of new drugs in different disease states, providing powerful support for drug development. By applying new drugs to the model, researchers can observe the degree of improvement of the drug on the disease phenotype and evaluate the efficacy and safety of the drug.
3. Individualized therapeutic strategy development: Genetic engineering homology model of InnoModels can simulate the genetic differences between different individuals, which provides strong support for individualized therapeutic strategy development. By screening and optimizing drugs according to the genetic characteristics of different individuals, researchers can develop more accurate and effective individualized treatment plans.
Summary
With the advantages of accurate simulation of disease mechanisms, high controllability, individualized treatment strategies, and shortened R&D cycle, InnoModels Biologics' genetically engineered homology models have demonstrated great potential and application value in the field of new drug discovery and development. With the continuous development of gene editing technology and the biomedical field, GMO homology models will play an even more important role in drug discovery and development in the future, and make a greater contribution to the cause of human health.

Keyword:

In the vast field of oncology and tumor immunopharmacodynamics research, InnoModels Biotechnology (Beijing) Ltd. has become a leader in the industry with its outstanding innovation ability and profound scientific research background. This company, co-founded by scientists from Novo Nordisk China R&D Center, Sino-US Crown and Shanghai Jiao Tong University Institute of Immunology, has been committed to building a stable domestic platform of humanized mouse models of the immune system (HIS) and human tumor xenografts (PDX) since its establishment in 2020, to provide new drug discovery and development companies, translational medicine researchers, and tumor patients with new-generation laboratory animal models for new drug discovery companies, translational medicine researchers, and tumor patients
In recent years, many breakthroughs have been made in the field of biomedical research, among which iHuPBMC-T technology is undoubtedly a shining star. As an innovative platform built by InnoModels Biotechnology (Beijing) Co., Ltd, iHuPBMC-T, with its unique technological advantages, shows great potential in optimizing the reconstruction of human peripheral blood single nucleated cell (PBMC) model and immuno-oncology research.
Recently, InnoModels Biotechnology (Beijing) Co., Ltd. has made a major breakthrough in the field of pharmaceutical technology, and successfully obtained a patent entitled “Method and application for the detection of immune system rebuilding ability of PBMC”. This patent not only adds a new footnote to the R&D strength of InnoModels Biotechnology in the field of biomedicine, but also provides a strong technical support for the promotion of drug research and development and the establishment of humanized experimental animal models
With the rapid development of biotechnology, the in-depth study of the immune system has become the key to new drug discovery, disease diagnosis and treatment. InnoModels Bio-technology (Beijing) Co., Ltd. provides strong support for researchers with its profound scientific background and advanced technology platform. Among them, the ELISpot platform of InnoModels Biotechnology has made a name for itself in the field of immunology research with its high sensitivity and multi-functionality
InnoModels' ADCC platform plays a pivotal role in advancing cancer treatment, and its unique technological advantages and innovative concepts have brought about a far-reaching impact on the field of tumor immunotherapy. The following is a detailed introduction of how the platform promotes the advancement of cancer treatment
In the field of tumor immunotherapy, complement-dependent cytotoxicity (CDC), as an important therapeutic mechanism, is gradually showing its great potential and value. In order to explore this mechanism more deeply, with its profound accumulation in the field of oncology and tumor immunopharmacodynamics CRO services, InnoModels Biotechnology (Beijing) Co., Ltd. has launched the CDC in vitro immune-tumor cell co-culture killing experimental platform, which provides researchers with a powerful and precise tool to help innovate cancer treatment
Previous page
1
2
43
  • Tel 15010000264
  • E-mail limy@imodels.tech
  • Tel 13810723384
  • Top

InnoModels Biotechnology (Beijing) Co., Ltd.

TEL:15010000264        13810723384

Address:Building 14, Life Valley, Shuangying West Road, Changping District, Beijing

Chuangmo Biotechnology (Beijing) Co., Ltd. Beijing ICP 222*** 98-1 Website Construction: China Enterprise Power Beijing Second Branch Company

北京中因科技有限公司

创模生物科技(北京)有限公司