创模生物科技(北京)有限公司

CN / En

NEWS

InnoModels BiotechnologyInnoModels Biotechnology: CDX Model - A Unique Tool to Reveal Tumor Properties

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-02 10:51
  • Views:

(Summary description)With the deepening of biomedical research, the establishment of tumor models is of great significance in understanding the mechanisms of tumor occurrence, development and treatment. As an important tumor model, the CDX model of InnoModels Biotechnology plays an important role in tumor research with its unique characteristics. In this paper, we will introduce the unique features of the CDX model of InnoModels Biotechnology in detail.

InnoModels BiotechnologyInnoModels Biotechnology: CDX Model - A Unique Tool to Reveal Tumor Properties

(Summary description)With the deepening of biomedical research, the establishment of tumor models is of great significance in understanding the mechanisms of tumor occurrence, development and treatment. As an important tumor model, the CDX model of InnoModels Biotechnology plays an important role in tumor research with its unique characteristics. In this paper, we will introduce the unique features of the CDX model of InnoModels Biotechnology in detail.

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-02 10:51
  • Views:
Information

With the deepening of biomedical research, the establishment of tumor models is of great significance in understanding the mechanisms of tumor occurrence, development and treatment. As an important tumor model, the CDX model of InnoModels Biotechnology plays an important role in tumor research with its unique characteristics. In this paper, we will introduce the unique features of the CDX model of InnoModels Biotechnology in detail.
1、Tumor heterogeneity is maintained
By transplanting artificially purified and multigenerationally cultured tumor cell lines into mice, the CDX model of InnoModels Biotechnology can maintain the heterogeneity of tumors. This heterogeneity reflects the genetic and phenotypic differences between different cells within the tumor, which helps researchers understand the biological characteristics of the tumor more deeply.
2. Stability of biological properties
The CDX model of InnoModels Biotechnology uses tumor cell lines that have been passed on many times, and these cell lines undergo strict quality control to ensure the stability of biological characteristics. This stability makes the CDX model more reliable in simulating tumor growth, invasion and metastasis.

 


3. Highly similar to human tumors
By simulating the growth environment and biological process of human tumors, the CDX model of Transmooker Biologicals has a high degree of similarity with human tumors in terms of gene expression, protein expression, and signaling pathways, etc. This makes the CDX model an ideal tool for researching tumors. This makes the CDX model an important tool for the study of tumorigenesis, development, therapeutic mechanism and drug screening.
4. High-throughput drug screening
The CDX model has the ability of high-throughput drug screening. By implanting tumor cell lines in mice, the inhibitory effect of drugs on tumor growth can be quickly assessed, providing an important basis for drug development. In addition, the model can also be used to study the drug resistance mechanism and the mechanism of tumor recurrence, providing new ideas and methods for clinical treatment.
5、Development of personalized treatment strategy
The InnoModels CDX model can be used to simulate the tumor characteristics of patients so as to formulate personalized treatment strategies. Through gene sequencing and phenotypic analysis of the patient's tumor tissues, we can screen out the suitable therapeutic drugs and solutions for the patient, and improve the therapeutic effect and survival rate of the patient.
In conclusion, the InnoModels Biotechnology CDX model has become an important tool in the field of tumor research due to its unique features of tumor heterogeneity retention, stability of biological properties, high similarity to human tumors, high-throughput drug screening ability, and the development of personalized treatment strategies. With the continuous progress of technology and the expansion of application scope, CDX model will play an increasingly important role in basic tumor research and clinical treatment.

Keyword:

In the vast field of oncology and tumor immunopharmacodynamics research, InnoModels Biotechnology (Beijing) Ltd. has become a leader in the industry with its outstanding innovation ability and profound scientific research background. This company, co-founded by scientists from Novo Nordisk China R&D Center, Sino-US Crown and Shanghai Jiao Tong University Institute of Immunology, has been committed to building a stable domestic platform of humanized mouse models of the immune system (HIS) and human tumor xenografts (PDX) since its establishment in 2020, to provide new drug discovery and development companies, translational medicine researchers, and tumor patients with new-generation laboratory animal models for new drug discovery companies, translational medicine researchers, and tumor patients
In recent years, many breakthroughs have been made in the field of biomedical research, among which iHuPBMC-T technology is undoubtedly a shining star. As an innovative platform built by InnoModels Biotechnology (Beijing) Co., Ltd, iHuPBMC-T, with its unique technological advantages, shows great potential in optimizing the reconstruction of human peripheral blood single nucleated cell (PBMC) model and immuno-oncology research.
Recently, InnoModels Biotechnology (Beijing) Co., Ltd. has made a major breakthrough in the field of pharmaceutical technology, and successfully obtained a patent entitled “Method and application for the detection of immune system rebuilding ability of PBMC”. This patent not only adds a new footnote to the R&D strength of InnoModels Biotechnology in the field of biomedicine, but also provides a strong technical support for the promotion of drug research and development and the establishment of humanized experimental animal models
With the rapid development of biotechnology, the in-depth study of the immune system has become the key to new drug discovery, disease diagnosis and treatment. InnoModels Bio-technology (Beijing) Co., Ltd. provides strong support for researchers with its profound scientific background and advanced technology platform. Among them, the ELISpot platform of InnoModels Biotechnology has made a name for itself in the field of immunology research with its high sensitivity and multi-functionality
InnoModels' ADCC platform plays a pivotal role in advancing cancer treatment, and its unique technological advantages and innovative concepts have brought about a far-reaching impact on the field of tumor immunotherapy. The following is a detailed introduction of how the platform promotes the advancement of cancer treatment
In the field of tumor immunotherapy, complement-dependent cytotoxicity (CDC), as an important therapeutic mechanism, is gradually showing its great potential and value. In order to explore this mechanism more deeply, with its profound accumulation in the field of oncology and tumor immunopharmacodynamics CRO services, InnoModels Biotechnology (Beijing) Co., Ltd. has launched the CDC in vitro immune-tumor cell co-culture killing experimental platform, which provides researchers with a powerful and precise tool to help innovate cancer treatment
Previous page
1
2
43
  • Tel 15010000264
  • E-mail limy@imodels.tech
  • Tel 13810723384
  • Top

InnoModels Biotechnology (Beijing) Co., Ltd.

TEL:15010000264        13810723384

Address:Building 14, Life Valley, Shuangying West Road, Changping District, Beijing

Chuangmo Biotechnology (Beijing) Co., Ltd. Beijing ICP 222*** 98-1 Website Construction: China Enterprise Power Beijing Second Branch Company

北京中因科技有限公司

创模生物科技(北京)有限公司