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InnoModels:Key Benefits of the InnoModels Biotechnology MHC Humanized Mouse Model

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-07 14:16
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(Summary description)The InnoModels Biotechnology MHC mouse model is an innovative technology in the biomedical field that provides a powerful tool for disease research, drug discovery and immunotherapy by accurately mimicking the human immune system. We will discuss the main advantages of this mouse model in detail below.

InnoModels:Key Benefits of the InnoModels Biotechnology MHC Humanized Mouse Model

(Summary description)The InnoModels Biotechnology MHC mouse model is an innovative technology in the biomedical field that provides a powerful tool for disease research, drug discovery and immunotherapy by accurately mimicking the human immune system. We will discuss the main advantages of this mouse model in detail below.

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-07 14:16
  • Views:
Information

The InnoModels Biotechnology MHC mouse model is an innovative technology in the biomedical field that provides a powerful tool for disease research, drug discovery and immunotherapy by accurately mimicking the human immune system. We will discuss the main advantages of this mouse model in detail below.
First, the MHC humanized mouse model has a high degree of immune similarity; MHC (major histocompatibility complex) plays a key role in regulating immune responses in the human body. Through gene editing technology, InnoModels Biotechnology has successfully replaced the MHC genes in mice with human MHC genes, enabling the immune system of these mice to mimic the human immune system to a large extent. This provides researchers with a more realistic experimental environment, making the results closer to the actual human situation.
Second, the MHC humanized mouse model has significant advantages in disease research. Due to the high degree of similarity in the immune system, this mouse model can more accurately simulate the onset and progression of a wide range of human diseases, including autoimmune diseases, tumors, infectious diseases, and so on. This enables researchers to conduct studies under conditions closer to the human physiological environment, thus providing a deeper understanding of disease pathogenesis and new ideas and methods for disease prevention and treatment.

 


In addition, the MHC humanized mouse model shows great potential for drug screening and immunotherapy. Traditional drug screening and immunotherapy methods are often limited by the differences between animal models and human physiological environments. The emergence of MHC humanized mouse models provides researchers with an experimental platform that is closer to the human physiological environment, making drug screening and immunotherapy research more accurate and efficient. This not only accelerates the drug development process, but also helps to improve the effectiveness and safety of drugs.
Last but not least, InnoModels' MHC humanized mouse models are also highly reproducible and controllable. Through gene editing technology, researchers can accurately control the MHC genotype and expression level of mice, thus realizing precise regulation of the immune system. This provides a guarantee for the stability and reliability of the experimental results, making the research results more reproducible.
In summary, InnoModels' MHC humanized mouse model has become an important tool in the field of biomedical research by virtue of its high degree of immunosimilarity, accuracy in disease research, potential for drug screening and immunotherapy, as well as reproducibility and controllability. With the continuous advancement of technology and the expansion of application areas, we have reason to believe that this mouse model will play an even more important role in the future and make greater contributions to human health.

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In the vast field of oncology and tumor immunopharmacodynamics research, InnoModels Biotechnology (Beijing) Ltd. has become a leader in the industry with its outstanding innovation ability and profound scientific research background. This company, co-founded by scientists from Novo Nordisk China R&D Center, Sino-US Crown and Shanghai Jiao Tong University Institute of Immunology, has been committed to building a stable domestic platform of humanized mouse models of the immune system (HIS) and human tumor xenografts (PDX) since its establishment in 2020, to provide new drug discovery and development companies, translational medicine researchers, and tumor patients with new-generation laboratory animal models for new drug discovery companies, translational medicine researchers, and tumor patients
In recent years, many breakthroughs have been made in the field of biomedical research, among which iHuPBMC-T technology is undoubtedly a shining star. As an innovative platform built by InnoModels Biotechnology (Beijing) Co., Ltd, iHuPBMC-T, with its unique technological advantages, shows great potential in optimizing the reconstruction of human peripheral blood single nucleated cell (PBMC) model and immuno-oncology research.
Recently, InnoModels Biotechnology (Beijing) Co., Ltd. has made a major breakthrough in the field of pharmaceutical technology, and successfully obtained a patent entitled “Method and application for the detection of immune system rebuilding ability of PBMC”. This patent not only adds a new footnote to the R&D strength of InnoModels Biotechnology in the field of biomedicine, but also provides a strong technical support for the promotion of drug research and development and the establishment of humanized experimental animal models
With the rapid development of biotechnology, the in-depth study of the immune system has become the key to new drug discovery, disease diagnosis and treatment. InnoModels Bio-technology (Beijing) Co., Ltd. provides strong support for researchers with its profound scientific background and advanced technology platform. Among them, the ELISpot platform of InnoModels Biotechnology has made a name for itself in the field of immunology research with its high sensitivity and multi-functionality
InnoModels' ADCC platform plays a pivotal role in advancing cancer treatment, and its unique technological advantages and innovative concepts have brought about a far-reaching impact on the field of tumor immunotherapy. The following is a detailed introduction of how the platform promotes the advancement of cancer treatment
In the field of tumor immunotherapy, complement-dependent cytotoxicity (CDC), as an important therapeutic mechanism, is gradually showing its great potential and value. In order to explore this mechanism more deeply, with its profound accumulation in the field of oncology and tumor immunopharmacodynamics CRO services, InnoModels Biotechnology (Beijing) Co., Ltd. has launched the CDC in vitro immune-tumor cell co-culture killing experimental platform, which provides researchers with a powerful and precise tool to help innovate cancer treatment
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InnoModels Biotechnology (Beijing) Co., Ltd.

TEL:15010000264        13810723384

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