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InnoModels Biotechnology: Unique Advantages of iHuPBMC-OncVax Model

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-09 13:51
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(Summary description)In the vast world of biomedical research, the humanized model of the immune system has always been a realistic and comprehensive experimental environment pursued by researchers. With the advancement of science and technology, iHuPBMC-OncVax model of InnoModels Biotechnology contributes to drug research and development with its unique advantages.

InnoModels Biotechnology: Unique Advantages of iHuPBMC-OncVax Model

(Summary description)In the vast world of biomedical research, the humanized model of the immune system has always been a realistic and comprehensive experimental environment pursued by researchers. With the advancement of science and technology, iHuPBMC-OncVax model of InnoModels Biotechnology contributes to drug research and development with its unique advantages.

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-09 13:51
  • Views:
Information

In the vast world of biomedical research, the humanized model of the immune system has always been a realistic and comprehensive experimental environment pursued by researchers. With the advancement of science and technology, iHuPBMC-OncVax model of InnoModels Biotechnology contributes to drug research and development with its unique advantages.
The greatest advantage of the iHuPBMC-OncVax model is its comprehensive immune cell reconstruction capability. Traditional PBMC models often only reconstruct human-derived T cells or NK cells, which undoubtedly limits their application in actual drug evaluation. The iHuPBMC-OncVax model, on the other hand, is able to reconstruct human T cells, B cells, NK cells, macrophages, and DC cells in mice, constructing a comprehensive and realistic immune system environment.
This comprehensive immune cell reconstruction provides more realistic and effective experimental conditions for drug evaluation. In the process of drug development, scientists need to evaluate the effects of drugs on the immune system through experiments to determine their efficacy and safety. The comprehensive immune system constructed by the iHuPBMC-OncVax model allows scientists to more accurately simulate the response of drugs in the human body, providing more reliable experimental data for drug development.

 


In addition, the iHuPBMC-OncVax model is able to fulfill the critical need of antigen delivery. In the traditional PBMC model, antigen presentation is not possible due to the lack of reconstruction of human-derived myeloid cells, which undoubtedly restricts its application in immunological research. The iHuPBMC-OncVax model, on the other hand, realizes the function of antigen presentation through the reconstruction of human-derived macrophages, which allows scientists to study the mechanism of drug effects on the immune system in greater depth.
In summary, the iHuPBMC-OncVax model of InnoModels Biotechnology provides a more realistic and effective experimental environment for drug discovery and development with its comprehensive immune cell reconstruction capability and antigen-presenting function. This unique advantage not only promotes a new chapter in drug discovery and development, but also injects new vitality into the development of biomedical research. We expect this model to play a greater role in future drug development and make greater contributions to human health.

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In the vast field of oncology and tumor immunopharmacodynamics research, InnoModels Biotechnology (Beijing) Ltd. has become a leader in the industry with its outstanding innovation ability and profound scientific research background. This company, co-founded by scientists from Novo Nordisk China R&D Center, Sino-US Crown and Shanghai Jiao Tong University Institute of Immunology, has been committed to building a stable domestic platform of humanized mouse models of the immune system (HIS) and human tumor xenografts (PDX) since its establishment in 2020, to provide new drug discovery and development companies, translational medicine researchers, and tumor patients with new-generation laboratory animal models for new drug discovery companies, translational medicine researchers, and tumor patients
In recent years, many breakthroughs have been made in the field of biomedical research, among which iHuPBMC-T technology is undoubtedly a shining star. As an innovative platform built by InnoModels Biotechnology (Beijing) Co., Ltd, iHuPBMC-T, with its unique technological advantages, shows great potential in optimizing the reconstruction of human peripheral blood single nucleated cell (PBMC) model and immuno-oncology research.
Recently, InnoModels Biotechnology (Beijing) Co., Ltd. has made a major breakthrough in the field of pharmaceutical technology, and successfully obtained a patent entitled “Method and application for the detection of immune system rebuilding ability of PBMC”. This patent not only adds a new footnote to the R&D strength of InnoModels Biotechnology in the field of biomedicine, but also provides a strong technical support for the promotion of drug research and development and the establishment of humanized experimental animal models
With the rapid development of biotechnology, the in-depth study of the immune system has become the key to new drug discovery, disease diagnosis and treatment. InnoModels Bio-technology (Beijing) Co., Ltd. provides strong support for researchers with its profound scientific background and advanced technology platform. Among them, the ELISpot platform of InnoModels Biotechnology has made a name for itself in the field of immunology research with its high sensitivity and multi-functionality
InnoModels' ADCC platform plays a pivotal role in advancing cancer treatment, and its unique technological advantages and innovative concepts have brought about a far-reaching impact on the field of tumor immunotherapy. The following is a detailed introduction of how the platform promotes the advancement of cancer treatment
In the field of tumor immunotherapy, complement-dependent cytotoxicity (CDC), as an important therapeutic mechanism, is gradually showing its great potential and value. In order to explore this mechanism more deeply, with its profound accumulation in the field of oncology and tumor immunopharmacodynamics CRO services, InnoModels Biotechnology (Beijing) Co., Ltd. has launched the CDC in vitro immune-tumor cell co-culture killing experimental platform, which provides researchers with a powerful and precise tool to help innovate cancer treatment
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InnoModels Biotechnology (Beijing) Co., Ltd.

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