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InnoModels Biotechnology: Introduction to the characteristics of dual humanized models

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-24 14:39
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(Summary description)In the field of biomedical research, animal models have always been an indispensable and important tool. However, traditional animal models often fail to fully simulate human physiological and pathological processes and have certain limitations. In order to solve this problem, InnoModels Biotechnology has launched the Dual Humanized Model. The model is based on human cells and tissues, constructed through advanced bioengineering technology, with a very high degree of simulation and practicability, opening up a new path for biomedical research.

InnoModels Biotechnology: Introduction to the characteristics of dual humanized models

(Summary description)In the field of biomedical research, animal models have always been an indispensable and important tool. However, traditional animal models often fail to fully simulate human physiological and pathological processes and have certain limitations. In order to solve this problem, InnoModels Biotechnology has launched the Dual Humanized Model. The model is based on human cells and tissues, constructed through advanced bioengineering technology, with a very high degree of simulation and practicability, opening up a new path for biomedical research.

  • Categories:Company news
  • Author:InnoModels
  • Origin:InnoModels
  • Time of issue:2024-04-24 14:39
  • Views:
Information

In the field of biomedical research, animal models have always been an indispensable and important tool. However, traditional animal models often fail to fully simulate human physiological and pathological processes and have certain limitations. In order to solve this problem, InnoModels Biotechnology has launched the Dual Humanized Model. The model is based on human cells and tissues, constructed through advanced bioengineering technology, with a very high degree of simulation and practicability, opening up a new path for biomedical research.
1、High simulation of human physiological and pathological processes
Dual humanized model adopts human cells and tissues, and realizes a high degree of simulation of human physiological and pathological processes through precise gene editing and tissue engineering technology. Such models can not only simulate human tissues and organs in terms of morphology, structure and function, but also simulate the pathogenesis and pathological changes of human diseases. This enables researchers to gain a deeper understanding of the nature and pathogenesis of diseases, providing more accurate and effective guidance for drug development and clinical treatment.
2、Reduce the moral and ethical controversy of animal experiments
Traditional animal models often involve animal experiments, which not only involve moral and ethical controversies, but also may lead to instability and unpredictability of experimental results. The dual humanized model, on the other hand, completely avoids these problems. It uses human cells and tissues without the need for animal experiments, which meets ethical and moral requirements and can provide more accurate and reliable research results.

 


3、Improve the efficiency of drug development and clinical treatment
The dual humanized model can simulate the pathogenesis and pathological changes of human diseases, providing more accurate and effective guidance for drug development and clinical treatment. By conducting drug screening and efficacy assessment on the model, researchers can screen potential drug candidates faster and conduct in-depth research and optimization on them. This will greatly shorten the drug development cycle and improve the success and efficiency of drug development. At the same time, the dual humanized model can also provide clinicians with more accurate treatment plans, improving treatment effects and patient survival rates.
4、Promote the development of personalized medicine
With the development of gene sequencing and bioinformatics and other technologies, personalized medicine has become an important trend in the field of biomedicine. As a model that highly simulates human physiological and pathological processes, dual humanization model can provide important support for personalized medicine. By constructing dual humanized models with individual differences, researchers can conduct accurate drug screening and efficacy assessment for different individuals' disease characteristics, providing more accurate and effective guidance for personalized medicine.
5. Challenges and prospects
Despite the many advantages and potentials of dual humanized models, they still face some challenges in practical applications. For example, it takes a lot of time and resources to construct models that highly simulate human physiological and pathological processes; at the same time, dual-sourced models may still have some limitations in simulating certain complex diseases. However, with the continuous progress of bioengineering and genomics technologies, it is believed that two-person modeling will be more widely used and developed in the future.
In conclusion, as a model with a high degree of simulation of human physiological and pathological processes, the InnoModels Biotechnology Two-Human Sourcing Model opens up a new path for biomedical research. It not only reduces the moral and ethical controversies of animal experiments and improves the efficiency of drug development and clinical treatment, but also provides important support for the development of personalized medicine. Despite some challenges, it is believed that with the continuous progress of technology and the expansion of application scope, dual humanized models will play a more important role in biomedical research.

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In the vast field of oncology and tumor immunopharmacodynamics research, InnoModels Biotechnology (Beijing) Ltd. has become a leader in the industry with its outstanding innovation ability and profound scientific research background. This company, co-founded by scientists from Novo Nordisk China R&D Center, Sino-US Crown and Shanghai Jiao Tong University Institute of Immunology, has been committed to building a stable domestic platform of humanized mouse models of the immune system (HIS) and human tumor xenografts (PDX) since its establishment in 2020, to provide new drug discovery and development companies, translational medicine researchers, and tumor patients with new-generation laboratory animal models for new drug discovery companies, translational medicine researchers, and tumor patients
In recent years, many breakthroughs have been made in the field of biomedical research, among which iHuPBMC-T technology is undoubtedly a shining star. As an innovative platform built by InnoModels Biotechnology (Beijing) Co., Ltd, iHuPBMC-T, with its unique technological advantages, shows great potential in optimizing the reconstruction of human peripheral blood single nucleated cell (PBMC) model and immuno-oncology research.
Recently, InnoModels Biotechnology (Beijing) Co., Ltd. has made a major breakthrough in the field of pharmaceutical technology, and successfully obtained a patent entitled “Method and application for the detection of immune system rebuilding ability of PBMC”. This patent not only adds a new footnote to the R&D strength of InnoModels Biotechnology in the field of biomedicine, but also provides a strong technical support for the promotion of drug research and development and the establishment of humanized experimental animal models
With the rapid development of biotechnology, the in-depth study of the immune system has become the key to new drug discovery, disease diagnosis and treatment. InnoModels Bio-technology (Beijing) Co., Ltd. provides strong support for researchers with its profound scientific background and advanced technology platform. Among them, the ELISpot platform of InnoModels Biotechnology has made a name for itself in the field of immunology research with its high sensitivity and multi-functionality
InnoModels' ADCC platform plays a pivotal role in advancing cancer treatment, and its unique technological advantages and innovative concepts have brought about a far-reaching impact on the field of tumor immunotherapy. The following is a detailed introduction of how the platform promotes the advancement of cancer treatment
In the field of tumor immunotherapy, complement-dependent cytotoxicity (CDC), as an important therapeutic mechanism, is gradually showing its great potential and value. In order to explore this mechanism more deeply, with its profound accumulation in the field of oncology and tumor immunopharmacodynamics CRO services, InnoModels Biotechnology (Beijing) Co., Ltd. has launched the CDC in vitro immune-tumor cell co-culture killing experimental platform, which provides researchers with a powerful and precise tool to help innovate cancer treatment
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InnoModels Biotechnology (Beijing) Co., Ltd.

TEL:15010000264        13810723384

Address:Building 14, Life Valley, Shuangying West Road, Changping District, Beijing

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