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Car-T in MHC/KO mice


Welcome to learn about our Car-T-MHC/KO therapy evaluation platform. We focus on providing a safer and more effective assessment environment for Car-T cell therapy.
Platform Features and Applications:
• MHC knockout mouse model• We use MHC knockout micemodel, providing a specific assessment environment for Car-T cell therapy. This model is designed to simulate the actual response of Car-T cells in the human body.
• Effectively reduce GVHD• By using MHC knockout mice, we effectively reduced the GVHD (graft-versus-host disease) caused by Car-T cells in mice, providing a safer environment for your research.
• Extend experimental window• Reducing the risk of GVHD not only improves the safety of the experiment but also extends the observation window, allowing you to more accurately assess the efficacy and durability of Car-T treatment.
Our Car-T-MHC/KO therapy evaluation platform provides a solid foundation for your cell therapy research and product development. If you have any questions or need further information, please feel free to Contact Us.

• Using B-NDG B2M KO mice, no GVHD response

• Up to 10 weeks of observation time, effectively validating the long-term efficacy of cellular immunotherapy

• Effectively observe the full lifecycle changes of CAR cells