Creatures

Cn /En

New drug development services

ADCC

Antibody-dependent cellular cytotoxicity (ADCC)
NK cells play a key role in the natural immune response, responsible for attacking cells marked by antibodies, such as tumor cells.ADCCIn the mechanism, antibodies bind to tumor cell antigens and interact with the activating Fc receptors of NK cells, triggering their cytotoxic activity.
Target cell selection
• Tumor cell lines: Suitable for a wide range of research and testing needs.
• Primary tumor cells: More accurately simulates the biological environment.
• Genetically engineered cell lines: Customized through genetic technology to meet specific research needs.
Source of effector cells
• Commercially sourced PBMCs: Standardized and suitable for most studies.
• PBMCs from clinical patients: More targeted, suitable for specific scenarios.
• NK92 cell line: Specifically designed for NK cell research.
Analysis and detection
• Flow cytometry detection: High precision in distinguishing effective target cells, providing accurate data for research.
• Apoptosis ratio: Using flow cytometry technology to accurately calculate the ratio of apoptotic cells, intuitively assessing the effect of ADCC.
Summary
Our ADCC platform provides you with comprehensive research tools, whether selecting the appropriate cell source or conducting precise analysis and detection, to meet your needs. Explore the potential role of ADCC in tumor therapy, starting from here.


Validate the in vitro ADCC efficacy of Rituximab on Raji cells (effector cells are NK92)

Chuangmo Biotechnology (Beijing) Co., Ltd.

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