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Humanized model of the immune system
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iHuPBMC-T
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iHuPBMC-NK
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iHuPBMC-B
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PBMC-LT
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CD34+ HSC
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Winn model
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iHuPBMC-MHC/KO
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iHuPBMC-OncVax
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PBMC mixed inoculation model
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In vivo tumor experimental platform
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CDX
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iHuPDX
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Non-GLP Toxicology
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PK/PD
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Brain in situ model
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Other in situ models
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Hematologic tumor model system inoculation
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Creation of high interstitial tumor models
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In vitro killing experiment platform
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Immune co-culture killing model
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CDC
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In vitro killing experiment platform
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IC50
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PDC High-Throughput In Vitro Pharmacodynamics
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3D organoids
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ADCC
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T cell-mediated killing experiment
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Mouse-derived immune system model
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Tumor vaccine
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Cell therapy
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In vitro testing platform
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Non-GLP Toxicology Platform
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Non-tumor model and drug efficacy evaluation platform
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Systematic Vaccination Model
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Non-tumor model and drug efficacy evaluation platform
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Skin injury model
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Stroke model
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Liver fibrosis model
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Diabetes model
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Gouty Arthritis (GA) Model
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Pulmonary fibrosis model
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Systemic lupus erythematosus (SLE) model
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Inflammatory Bowel Disease (IBD) model
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Rheumatoid Arthritis (RA) Model
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PDX model
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PDX model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Human breast cancer
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Esophageal cancer in humans
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Human gastric cancer
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Colorectal cancer
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Human liver cancer
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Bile duct cancer
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Gallbladder cancer
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Human pancreatic cancer
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Human kidney cancer
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Human Bladder Cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer in women
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Human Ovarian Cancer
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Human skin cancer
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sarcoma
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Human Nervous System Cancer
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Embryonal carcinoma
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Human Lymphoma
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Human leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other people
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CDX model
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CDX model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Human breast cancer
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Esophageal cancer in humans
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Human gastric cancer
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Colorectal cancer
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Human liver cancer
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Bile duct cancer
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Gallbladder cancer
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Human pancreatic cancer
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Human kidney cancer
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Human Bladder Cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer in women
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Human Ovarian Cancer
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Human skin cancer
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sarcoma
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Human Nervous System Cancer
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Embryonal carcinoma
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Human Lymphoma
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Human leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other people
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Homogeneous Model
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Homogeneous Model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Breast cancer
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Stomach cancer
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Liver cancer
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Bile duct cancer
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Gallbladder cancer
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Pancreatic cancer
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Kidney cancer
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Bladder cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer
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Ovarian cancer
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Esophageal cancer
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Skin cancer
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sarcoma
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Nervous System Cancer
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Embryonal carcinoma
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Lymphoma
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Leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other
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Colorectal cancer
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News Center
——
InnoModels Biotechnology iHuPDX Platform
Author:
InnoModels
Release time:
2024-09-03
In the biomedical field, innovation is a key driver for technological advancement and clinical application. With its iHuPDX (Individualized Human Patient-Derived Xenograft) platform, InnoModels Biotechnology (Beijing) Co., Ltd. is bringing unprecedented changes to cancer research and treatment. iHuPDX platform not only demonstrates InnoModels BioTech's profound strength in the field of personalized medicine, but also provides new hopes and possibilities for tumor treatment. The iHuPDX platform not only demonstrates the profound strength of Thermo Scientific in the field of personalized medicine, but also provides new hope and possibilities for tumor treatment.
Background and Technical Principle of iHuPDX Platform
The iHuPDX platform is a xenotransplantation technology based on patients' individual tumor cells, aiming to establish a more realistic and individualized cancer model. The technology collects cancer tissue samples from patients and transplants them into animals such as mice to form individualized transplanted tumors. This highly individualized disease model can more accurately simulate the biological characteristics of a patient's tumor, such as growth, metastasis and drug response, providing strong support for precision medicine.
Advantages and applications of iHuPDX platform
1. Accurately simulate patients' tumor characteristics
Traditional tumor models are often based on standardized cell lines or tissue samples, which cannot fully reflect the uniqueness of patient tumors. The iHuPDX platform, on the other hand, is derived directly from the patient's tumor cells, and is therefore able to more accurately simulate the growth and metastasis of the patient's tumor. This individualized disease model not only helps doctors to understand the patient's tumor characteristics more comprehensively, but also provides an important basis for the development of personalized treatment plans.
2. Drug response prediction
Due to the high degree of similarity between the iHuPDX platform and the patient's tumor, researchers can test the response of different drugs to a specific patient's tumor on the model, thus predicting the drug's efficacy and possible side effects in the patient. This predictive capability enables physicians to select the most appropriate drug combination and dosage for a patient before treatment, increasing the success rate of treatment and reducing unnecessary risks.
3. Broad Application Areas
The iHuPDX platform has a wide range of applications in the fields of cancer research, drug development, tumor biology research, and tumor immunity-related research. It not only provides researchers with experimental animal models that are closer to the clinic, but also promotes the development of new drug development and translational medicine. Through this platform, researchers are able to explore more deeply the differences in tumor heterogeneity among different patients, reveal the diversity of cancers, and provide important information for the development of individualized treatment strategies.

Strength and Future Prospects of InnoModels Biotechnology
Founded by scientists from Novo Nordisk China R&D Center, Sino-US Champion, and the Institute of Immunology of Shanghai Jiaotong University, InnoModels Biotechnology (Beijing) Ltd. is endowed with rich scientific research resources and strong technical support. With a stable domestic platform of humanized mouse model of immune system (HIS) and human tumor xenograft platform (PDX), the company is committed to providing the most clinically referenced preclinical research support for oncology and tumor immunotherapy innovators.
InnoModels Biotechnology is confident in the future of the iHuPDX platform. With the deepening of biomedical research and continuous technological innovation, the iHuPDX platform is expected to play a more important role in the field of personalized medicine. In the future, we can expect to see more research results and application scenarios related to the iHuPDX platform, which will bring hope and gospel to more patients.
Conclusion
With its unique advantages and wide range of application areas, iHuPDX platform of InnoModels Biotechnology is leading the new trend of personalized medicine. By providing highly individualized tumor models for medical research and drug development, the iHuPDX platform brings new possibilities for precision cancer treatment. InnoModels Biotechnology will continue to devote itself to promoting the development of this technology, providing patients with more effective treatment options, and contributing to the continuous progress of the biomedical field.
InnoModels Biotechnology (Beijing) Co., Ltd.
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TEL: +86 15711355061
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E-mail: xuyl@imodels.tech
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Address: Building 14, No. 79 West Shuangying Road, Changping District, Beijing
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