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Humanized model of the immune system
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iHuPBMC-T
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iHuPBMC-NK
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CD34+ HSC
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Winn model
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iHuPBMC-MHC/KO
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iHuPBMC-OncVax
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PK/PD
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Brain in situ model
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Hematologic tumor model system inoculation
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Creation of high interstitial tumor models
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In vitro killing experiment platform
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Immune co-culture killing model
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CDC
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In vitro killing experiment platform
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IC50
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PDC High-Throughput In Vitro Pharmacodynamics
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3D organoids
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ADCC
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T cell-mediated killing experiment
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Mouse-derived immune system model
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Tumor vaccine
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Cell therapy
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In vitro testing platform
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Non-GLP Toxicology Platform
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Non-tumor model and drug efficacy evaluation platform
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Systematic Vaccination Model
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Non-tumor model and drug efficacy evaluation platform
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Skin injury model
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Stroke model
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Liver fibrosis model
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Diabetes model
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Gouty Arthritis (GA) Model
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Pulmonary fibrosis model
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Systemic lupus erythematosus (SLE) model
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Inflammatory Bowel Disease (IBD) model
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PDX model
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PDX model
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Head and neck cancer
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Human breast cancer
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Esophageal cancer in humans
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CDX model
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CDX model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Esophageal cancer in humans
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Human gastric cancer
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Human liver cancer
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Bile duct cancer
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Human pancreatic cancer
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Human kidney cancer
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Human Bladder Cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer in women
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Human Ovarian Cancer
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Human skin cancer
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sarcoma
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Human Nervous System Cancer
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Embryonal carcinoma
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Human Lymphoma
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Human leukemia
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Multiple Myeloma
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Adrenal gland
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Homogeneous Model
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Homogeneous Model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Breast cancer
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Stomach cancer
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Liver cancer
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Bile duct cancer
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Gallbladder cancer
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Pancreatic cancer
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Kidney cancer
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Bladder cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer
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Ovarian cancer
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Esophageal cancer
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Skin cancer
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sarcoma
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Nervous System Cancer
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Embryonal carcinoma
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Lymphoma
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Leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other
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Colorectal cancer
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News Center
——
Functionality of the 3D organoid platform of InnoModels Biotechnology
Author:
InnoModels
Release time:
2024-08-09
In the fast-changing world of biotechnology, InnoModels Biotechnology (Beijing) Co., Ltd. has brought breakthroughs in the fields of new drug discovery, disease modeling and personalized medicine with its innovative 3D organoid platform. Based on the clinical tumor biosample library, the platform realizes the seamless integration of the whole process from in vitro high-throughput screening to in vivo research through advanced technological means, providing strong support for researchers.
Rapid Prediction and Drug Screening
A core function of the 3D organoid platform of InnoModels Biotechnology is the rapid prediction of drug efficacy in the clinic. This feature enables researchers to obtain critical feedback in the early stages of drug development so that they can make timely adjustments to their R&D strategies. In addition, the platform is able to screen compounds with higher development potential from a wide range of alternatives, greatly optimizing resource allocation and accelerating the process of new drug development.
Model Screening and Efficacy Comparison
On the basis of drug screening, the platform can also select the most suitable model for subsequent in vivo experiments based on the response of the drug to the model. This feature ensures the consistency and reliability of experimental data, providing researchers with more accurate experimental results. At the same time, by comparing with counterpart drugs or clinical therapeutic drugs, the platform can intuitively demonstrate the differences in efficacy and effective models, providing a strong basis for further optimization of drugs.
Disease specificity analysis and drug resistance analysis
For different types of cancers, the 3D organoid platform from InnoModels Biotechnology is able to compare the efficacy differences between different cancer model cohorts to determine the best indication for a drug. This feature is important for improving drug targeting and effectiveness. In addition, the platform is able to differentiate models into effective and resistant models based on efficacy data, and based on the differences in genetic features between models and before and after treatment, it can deeply explore the mechanism of action and resistance of drugs to provide more scientific guidance for clinical drug use.

Biomarker Discovery
The 3D organoid platform of InnoModels also has the function of biomarker discovery. By categorizing models according to their efficacy and analyzing the differences in genetic characteristics of different groups based on histology, researchers can find biomarkers that can predict drug efficacy. These biomarkers not only help in the precise treatment of drugs, but also provide an important reference for the early diagnosis and prognosis assessment of diseases.
Advantages of 3D organoid technology
The 3D organoid platform of InnoModels Biotechnology has such powerful functions thanks to its 3D organoid technology. Compared with traditional 2D cell culture and animal experiments, 3D organoids can better simulate the natural physiological processes of cells, providing more accurate models of human disease development and more clinically valuable research results. In addition, 3D organoids have realistic microanatomical structures and organ-specific cell types, and can even mimic part of an organ's function, making the research results closer to the real situation.
Summarization
In summary, the 3D organoid platform of InnoModels Biotechnology has shown great potential and value in the field of biotechnology by virtue of its powerful functions such as rapid prediction, drug screening, model screening, efficacy comparison, disease specificity analysis, drug resistance analysis, and biomarker discovery. The platform not only accelerates the process of new drug development and improves the targeting and effectiveness of drugs, but also provides powerful support for early diagnosis, prognosis assessment and personalized treatment of diseases. In the future, with the continuous progress and improvement of the technology, the 3D organoid platform will certainly play an even more important role in the field of biotechnology.
InnoModels Biotechnology (Beijing) Co., Ltd.
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TEL: +86 15711355061
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E-mail: xuyl@imodels.tech
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Address: Building 14, No. 79 West Shuangying Road, Changping District, Beijing
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