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IC50
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PDC High-Throughput In Vitro Pharmacodynamics
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3D organoids
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ADCC
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T cell-mediated killing experiment
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Mouse-derived immune system model
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Systematic Vaccination Model
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Skin injury model
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Stroke model
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Diabetes model
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Gouty Arthritis (GA) Model
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Systemic lupus erythematosus (SLE) model
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PDX model
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CDX model
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CDX model
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sarcoma
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Homogeneous Model
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Homogeneous Model
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sarcoma
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Embryonal carcinoma
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Lymphoma
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Leukemia
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Multiple Myeloma
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Adrenal gland
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Other
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Colorectal cancer
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News Center
——
What are the applications of InnoModels Bio's Luminex platform?
Author:
InnoModels
Release time:
2024-07-19
The applications of the InnoModels BioLuminex platform are mainly focused on pharmaceutical R&D, especially in oncology and tumor immunology preclinical drug evaluation. With its unique technical features and advantages, the platform provides powerful technical support for researchers. The following are the main applications of the platform:
1. Multiplexed quantitative analysis of cytokines:
The Luminex platform is capable of accurately determining the levels of a wide range of cytokines, including multiple quantitative analyses in cytokine release assays, providing comprehensive data support for evaluating the effectiveness of immunotherapy.
With only 25 μL of serum sample, quantitative testing of up to 50 indicators can be accomplished, greatly improving experimental efficiency.
2. Drug screening and evaluation:
The Luminex platform plays an important role in drug screening and evaluation, providing researchers with precise and multiplexed data on the effects of drugs on cytokines and other immune response-related proteins.
For example, the Luminex Mouse Multifactor Assay Kit was used to quantify the expression of cytokines in serum to aid in the evaluation of the biosafety of novel nanoparticles in a study at Shaw Hospital, Zhejiang University School of Medicine.

3. Preclinical evaluation of tumor immunotherapy:
The Luminex platform is particularly well suited for preclinical evaluation of tumor immunotherapies by detecting changes in cytokines and other immune response-associated proteins, providing investigators with important information about drug efficacy and safety.
4. Broad research areas:
In addition to oncology and tumor immunology research, the Luminex platform is also applicable to other research areas, such as pathogenesis research of inflammation, infection, endocrine, digestive system and other diseases, as well as evaluation of drug activity/mechanism of action.
5. High-throughput generic clinical trials:
In the early stage of new drug development, the Luminex platform is combined with organoid/PDC and other in vitro platforms to conduct high-throughput generic clinical efficacy testing to meet the needs of clinical commercial value prediction of new drugs and subsequent development strategy formulation.
In summary, with its unique technical features and wide range of applications, the Luminex platform of InnoModels Biotechnology provides powerful support to researchers in the field of pharmaceutical R&D, and especially plays an important role in preclinical drug evaluation of oncology and tumor immunology.
InnoModels Biotechnology (Beijing) Co., Ltd.
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TEL: +86 15711355061
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E-mail: xuyl@imodels.tech
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Address: Building 14, No. 79 West Shuangying Road, Changping District, Beijing
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