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InnoModels Biotechnology: What are the features of PDC high-throughput in vitro drug efficacy platform

Author:

InnoModels

Release time:

2024-04-29

With the rapid development of biotechnology, the field of drug discovery and development is ushering in unprecedented changes. With its unique technical advantages, InnoModels Biotechnology PDC high-throughput in vitro drug efficacy platform brings a brand-new breakthrough in the field of drug research and development. The platform utilizes advanced technological means to conduct rapid, efficient and accurate in vitro drug efficacy assessment, which greatly improves the efficiency and success rate of drug R&D and injects new vitality into the development of the pharmaceutical industry.
1、Highly consistent primary cells
InnoModels Biotechnology PDC high-throughput in vitro drug efficacy platform uses the digestion products of PDX model to obtain highly consistent primary cells with patients. Such cells have complex cell subpopulations and biological characteristics, which can realistically simulate the drug response environment in the human body, making the drug's action and response closer to the clinical situation. At the same time, highly consistent primary cells provide more reliable experimental data for drug development and help researchers more accurately assess the efficacy and safety of drugs.
2. Pharmacodynamic response and clinical relevance
InnoModels Biotechnology PDC high-throughput in vitro drug efficacy platform is not only applicable to the screening of test drugs and models, but also capable of predicting the clinical efficacy of drugs. By comparing the subject drug with counterpart drugs (e.g., drugs with similar mechanism of action or standardized therapeutic drugs), the platform can predict the clinical value of the drug and provide powerful decision support for drug development. In addition, the platform can also compare the effective rates of different cancer type models through multi-dimensional applications, determine the indications of drugs, and search for biomarkers predicting drug efficacy through the differences in genetic characteristics between sensitive and resistant models, providing an important basis for personalized treatment.

3、Multi-parameter assay and multi-cell type support
The PDC high-throughput in vitro drug efficacy platform adopts advanced PDC technology, allowing researchers to simultaneously assess multiple cell phenotypic parameters, such as cell proliferation, cell cycle, apoptosis, etc., to provide a more comprehensive understanding of drug effects. In addition, the platform supports the application of multiple cell types, including tumor cells, primary cells, etc., which is suitable for drug research in different disease areas. This multi-parameter determination and multi-cell type support makes the drug development process more accurate and comprehensive, providing researchers with more dimensional research data.
4、High throughput screening and high efficiency
InnoModels Biotechnology PDC high-throughput in vitro drug efficacy platform is able to screen a large number of drugs in a short period of time, which improves the research efficiency. Compared with the traditional in vivo experimental platform, the experimental cycle of the in vitro experimental platform can be shortened by more than three times, and at the same time, the flux of the tested drugs can be increased by more than five times, while the cost is only a fraction of the in vivo experiments. This high-throughput screening feature makes the drug development process more efficient and rapid, saving a lot of time and money for researchers and accelerating the drug development process.
In conclusion, InnoModels' PDC high-throughput in vitro drug discovery platform brings a brand new breakthrough in the field of drug discovery and development with its high consistency of primary cells, clinical relevance of drug discovery, multi-parameter assay and multi-cell type support, as well as high-throughput screening and high efficiency. The platform provides researchers with a more accurate, comprehensive and efficient drug discovery and development tool, which helps to promote the rapid development of the pharmaceutical industry and make important contributions to human health.

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InnoModels Biotechnology (Beijing) Co., Ltd.

TEL: +86 15711355061
E-mail: xuyl@imodels.tech
Address: Building 14, No. 79 West Shuangying Road, Changping District, Beijing

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