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Humanized model of the immune system
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iHuPBMC-T
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iHuPBMC-NK
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iHuPBMC-B
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PBMC-LT
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CD34+ HSC
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Winn model
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iHuPBMC-MHC/KO
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iHuPBMC-OncVax
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PBMC mixed inoculation model
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In vivo tumor experimental platform
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CDX
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iHuPDX
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Non-GLP Toxicology
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PK/PD
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Brain in situ model
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Other in situ models
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Hematologic tumor model system inoculation
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Creation of high interstitial tumor models
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In vitro killing experiment platform
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Immune co-culture killing model
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CDC
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In vitro killing experiment platform
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IC50
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PDC High-Throughput In Vitro Pharmacodynamics
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3D organoids
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ADCC
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T cell-mediated killing experiment
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Mouse-derived immune system model
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Tumor vaccine
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Cell therapy
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In vitro testing platform
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Non-GLP Toxicology Platform
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Non-tumor model and drug efficacy evaluation platform
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Systematic Vaccination Model
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Non-tumor model and drug efficacy evaluation platform
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Skin injury model
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Stroke model
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Liver fibrosis model
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Diabetes model
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Gouty Arthritis (GA) Model
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Pulmonary fibrosis model
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Systemic lupus erythematosus (SLE) model
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Inflammatory Bowel Disease (IBD) model
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Rheumatoid Arthritis (RA) Model
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PDX model
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PDX model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Human breast cancer
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Esophageal cancer in humans
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Human gastric cancer
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Colorectal cancer
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Human liver cancer
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Bile duct cancer
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Gallbladder cancer
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Human pancreatic cancer
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Human kidney cancer
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Human Bladder Cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer in women
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Human Ovarian Cancer
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Human skin cancer
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sarcoma
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Human Nervous System Cancer
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Embryonal carcinoma
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Human Lymphoma
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Human leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other people
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CDX model
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CDX model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Human breast cancer
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Esophageal cancer in humans
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Human gastric cancer
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Colorectal cancer
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Human liver cancer
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Bile duct cancer
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Gallbladder cancer
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Human pancreatic cancer
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Human kidney cancer
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Human Bladder Cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer in women
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Human Ovarian Cancer
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Human skin cancer
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sarcoma
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Human Nervous System Cancer
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Embryonal carcinoma
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Human Lymphoma
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Human leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other people
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Homogeneous Model
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Homogeneous Model
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Head and neck cancer
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Eye cancer
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Lung cancer
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Breast cancer
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Stomach cancer
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Liver cancer
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Bile duct cancer
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Gallbladder cancer
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Pancreatic cancer
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Kidney cancer
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Bladder cancer
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Ureteral cancer
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Prostate cancer
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Uterine cancer
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Cervical cancer
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Ovarian cancer
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Esophageal cancer
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Skin cancer
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sarcoma
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Nervous System Cancer
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Embryonal carcinoma
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Lymphoma
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Leukemia
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Multiple Myeloma
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Adrenal gland
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Mesothelioma
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Other
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Colorectal cancer
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News Center
——
InnoModels Biotechnology: Key Features of MHC Humanized Mouse Models
Author:
InnoModels
Release time:
2024-03-28
With the rapid development of biotechnology, mankind's understanding of diseases and means of treatment continue to progress. As a major innovation in the field of biomedical research, the InnoModels Biotechnology MHC humanized mouse model is gradually unraveling the mystery of complex diseases and injecting new vitality into medical progress.
MHC, or major histocompatibility complex, is the key to the human immune system's ability to recognize "self" and "not-self". InnoModels has successfully implanted the human MHC gene into mice, creating a humanized mouse model of MHC. This mouse model not only has the ability to highly mimic the human immune system, but also has physiological functions and disease responses that are closer to those of humans, providing a more accurate tool for disease research.

The main features of the MHC humanized mouse model are:
1. Highly mimic the human immune system: Through gene editing technology, the MHC genes of mice are replaced with human MHC genes, enabling their immune systems to more realistically mimic human immune responses. This is of great significance for the study of autoimmune diseases, infectious diseases and tumor immunity.
2. Predictability of disease models: Since the immune system of mice is closer to that of human beings, the disease models established using MHC humanized mouse models are more predictable. This is important for drug development and clinical trial design.
3. Improvement of drug development efficiency: Using MHC humanized mouse models for drug screening and effect evaluation can more accurately predict drug responses in the human body, thus shortening the drug development cycle and improving R&D efficiency.
4. Potential for personalized medicine: The MHC humanized mouse model can also be used to simulate the differences in immune responses of different individuals, providing the possibility of personalized medicine. Through the analysis of the model, it can be used to more accurately predict an individual's response to the drug and the therapeutic effect.
In conclusion, the successful creation of the InnoModels Biotechnology MHC humanized mouse model not only provides a powerful tool for biomedical research, but also offers new ideas and methods for drug development and clinical treatment. In the future, with the continuous improvement and optimization of this technology, we have reason to believe that it will contribute more to human health and medical progress.
InnoModels Biotechnology (Beijing) Co., Ltd.
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TEL: +86 15711355061
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E-mail: xuyl@imodels.tech
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Address: Building 14, No. 79 West Shuangying Road, Changping District, Beijing
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